Human Spiral Artery Renin-Angiotensin System

Human spiral artery renin-angiotensin system.

Pregnancy induces uterine spiral arteries to remodel into dilated uteroplacental vessels by an unknown mechanism called "physiological change." In women who develop preeclampsia, however, many spiral arteries remain unchanged or develop medial hyperplasia and atherosis. We recently demonstrated that angiotensinogen is expressed by remodeling spiral arteries in first-trimester decidua. We hypoth...

Renin-angiotensin system and unilateral ureteral obstruction

Unilateral ureteral obstruction (UUO) is a clinical scenario that leads to obstructive nephropathy. UUO alters the expression of many mediators in the ipsilateral kidney. Renin-angiotensin system (RAS) is involved in UUO. Angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7) as the main arms of RAS influence kidney function which may alter by UUO. Ang II via Ang II receptor subtypes I (AT1R) ...

Renin - Angiotensin - Aldosterone System

Chronic heart failure (CHF) is associated with endothelial dysfunction. Activation of the renin-angiotensin-aldosterone system (RAAS) is believed to be important in the deterioration of endothelial dysfunction in CHF through stimulation of oxidative stress. Whereas angiotensin-converting enzyme inhibitors (ACE-I) improve endothelial function in CHF, the effects of angiotensin II AT 1-receptor b...

Renin - Angiotensin - Aldosterone System

http://jra.sagepub.com/content/10/1/24 The online version of this article can be found at: DOI: 10.1177/1470320309104067 2009 10: 24 Journal of Renin-Angiotensin-Aldosterone System Manuel Labiós, Marcial Martínez, Francisco Gabriel, Victoria Guiral, Francisco Dasi, Belén Beltrán and Anna Muñoz patients: effects of eprosartan treatment Superoxide dismutase and catalase anti-oxidant activity in l...

Brain Renin–Angiotensin System